Altogen Services provides life science research services to pharmaceutical, biotechnology, and academic institutions worldwide, offering a complete solution for RNAi (gene silencing) projects, generation of stable cell lines, cloning, protein expression, reporter assay development, cell culture, transient and stable transfection, functional library screening (siRNA and microRNA), and various other biology and pharmacology services. Altogen Services located in Austin, TX.

The company’s scientists bring years of extensive experience and expertise to pre-clinical studies, cell and molecular biology, and RNAi. Altogen Services offers a wide range of custom research services to meet the unique needs of clients. The company’s technical support and quality control teams ensure and support the high-quality products and services.

Altogen Services provides instant on-line quotation (techserv@altogen.com), comprehensive service packages, and highly competitive prices.

Our Standard Research Services include:

• RNAi Services, Gene targeting
• Liposome formulation, Custom liposome encapsulation
• Tissue culture services, Cell-based assay development
• Pharmaceuticals testing in vitro and in vivo
• PCR cloning and vector construction
• Stem cells isolation and characterization
• Generation of stable cell lines (protein overexpression)
• Generation of stable RNAi cell lines (stably expressing shRNA targeting gene of interest)
• Genome-wide library screening (small molecule, siRNA, miRNA)
• In Vitro Functional testing of siRNA gene silencing efficiency (50+ cell lines/primary cultures available)
• DNA and RNA isolation and purification
• Cell-based assays: cytotoxicity, apoptosis, cell cycle arrest, etc
• Protein services
• Transient and stable transfection services
• siRNA, shRNA, miRNA design and synthesis
• Oligonucleotide (siRNA, miRNA) chemical modification to enhance stability in vivo
• Endotoxin and RNase contamination testing
• Quantitation of siRNA/shRNA gene silencing effect by qRT-PCR and Western Blot
• Transfection reagent optimization and development
• Cryopreservation service
• Custom reporter gene assays

siRNA Delivery - In Vivo Transfection Kits

CRO Pre-clinical Research Services: Xenograft animal models

GLP-compliant Cell Banking services

Generation of Stably Expressing Cell Lines in 28 Days

Stable RNAi Cell Line Generation: Stable Gene Knockdown

In Vivo siRNA Delivery: Tissue-targeted siRNA

Encapsulation of Protein, RNA, mRNA, and DNA Molecules into Liposomes

Once the details of the project are known, Altogen Services can provide customers with an immediate price quote (contact e-mail: techserv@altogen.com). Please note that experimental details allow accurate quotes and timeline estimates.